DMT-2'-O-TBDMS-G(dmf)-CE Phosphoramidite Nucleotides "RNA synthesis using 2′-O-(tert-butyldimethylsilyl) protection

"RNA synthesis using 2′-O-(tert-butyldimethylsilyl) protection

" Molecular and Cellular Probes 8

5) that enhances compatibility with biochemical and enzymatic assays

Hironori Adachi

DMT-2'-O-TBDMS-G(dmf)-CE Phosphoramidite Nucleotides "RNA synthesis using 2′-O-(tert-butyldimethylsilyl) protectionDMT 2' O TBDMS G(dmf) CE Phosphoramidite is a protected ribonucleoside building block used for solid phase RNA oligonucleotide synthesis. It contains a 5' dimethoxytrityl (DMT) protecting group for 5' hydroxyl protection, a 2' O tert butyldimethylsilyl (TBDMS) protecting group for 2' hydroxyl protection, a cyanoethyl (CE) protecting group on phosphite, and a dimethylformamidyl (dmf) base protecting group on guanine. TBDMS offers excellent stability