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Once the T cell receptor binds its specific antigen Lck phosphorylates the cytoplasmic CD3 and ζ-chains of the TCR complex which initiates a cascade of phosphorylation eventually leading to activation of transcription factors like NFAT
coli Molecular Weight 19kDa (Reducing)
but interacts with C-type lectin-like CLEC2 glycoproteins
cytoskeletal rearrangement
IL-21 Protein, Rat Proteins and Enzymes Once the T cell receptorProduct Specification Species Rat Synonyms Interleukin 21, IL 21 Accession A3QPB9 Amino Acid Sequence His18 Ser146 Expression System E. coli Molecular Weight 15kDa Purity 95% by SDS PAGE&RP HPLC Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 20mM Tris, 400mM NaCl, pH8. 0 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid centrifugation.
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